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Mice Deficient in the Enzyme MMP7, That Cleaves Prepro- α\alpha -Defensin to the Active

question 15

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Mice deficient in the enzyme MMP7, that cleaves prepro- α\alpha -defensin to the active α\alpha -defensin, show an increased susceptibility to the enteric pathogen, Salmonella typhimurium. The cell type in the gastrointestinal (GI) epithelium most likely to express the highest levels of MMP7 is:

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