When Vesicular Stomatitis Virus (VSV) Is Used to Infect Mice

question 6

Essay

When vesicular stomatitis virus (VSV) is used to infect mice via footpad injection, viral particles are trapped in the draining lymph node (the popliteal lymph node) within 5 minutes of injection. These viral particles are then retained in the lymph node for many hours, where they can be visualized on cells that are interacting with B cells. The cells retaining the viral particles in the lymph node are not tissue-resident dendritic cells that have migrated to the lymph node with the virus, as this process takes much longer than 5 minutes. In which region of the lymph node would you expect to find the trapped viral particles and on which cells?

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Definitions:

Department A

A specific segment or division within an organization that focuses on a particular set of tasks or responsibilities.

Equivalent Units

A concept in cost accounting used to equate units of production in various stages of completion to a number of fully completed units.

Direct Labour

This refers to the work done by employees who directly contribute to the manufacturing or production process of a company's goods or services.

Factory Overhead

All costs related to manufacturing that are not direct materials or direct labor expenses.