When Macrophages in the Lung Are Infected with an Intracellular

question 18

Multiple Choice

When macrophages in the lung are infected with an intracellular bacterium, such as Mycobacterium tuberculosis, they are activated by the interactions of their pattern recognition receptors with the microbe. These activated macrophages will then:

• A) Migrate to the marginal sinus of the draining lymph node to activate naive CD4 T cells
• B) Increase their phagocytic properties to scavenge dead and dying neighboring cells
• C) Migrate to the liver where they will remove dying cells from the blood
• D) Migrate to the red pulp of the spleen where they will remove immune complexes from the circulation
• E) Up-regulate MHC class II and B7 molecules to amplify CD4 T cell responses in the lung

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Definitions:

Histogram

A graphical representation of the distribution of numerical data, where the data is divided into bins and the frequency of the data in each bin is depicted through the height of the bar.

IQR

Interquartile Range, a measure of variability that indicates the spread of the middle 50% of a dataset.

Standard Deviation

An indicator of the range of variability or spread within a series of numbers, showing the extent to which these numbers deviate from the average.

Mean Price

Mean price is the average price of a set of goods or services, calculated by dividing the total price by the number of items.