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While CD28 Co-Stimulation Is Important for the Initial Activation of Naive

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While CD28 co-stimulation is important for the initial activation of naive T cells, other co-stimulatory molecules function at later stages of the T cell response. Several of these other co-stimulatory molecules are members of the TNF-receptor family, and function by activating the transcription factor, NF κ\kappa B. Therefore, stimulation of these co-stimulatory TNF-receptors on activated T cells is likely to:


Definitions:

Bladder Training

A method used to help individuals gain better control over their bladder, typically involving scheduled urination and exercises to strengthen muscles.

Voiding Interval

The time span between individuals' urination, which is important for assessing urinary health and function.

Stress Incontinence

Stress incontinence is the involuntary leakage of urine during activities that increase intra-abdominal pressure, such as coughing, sneezing, or lifting, due to weakened pelvic floor muscles.

Urge Incontinence

A condition characterized by the sudden, intense need to urinate followed by an involuntary loss of urine.

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