Several Effector T Cell Functions Are Mediated by Cell Surface

question 19

Multiple Choice

Several effector T cell functions are mediated by cell surface molecules on the effector cell interacting with binding partners on the target cells. In the case of the CD40-CD40 ligand interaction, effector CD4 T cells express CD40 ligand, which binds to CD40 target cells. Individuals with a genetic deficiency in CD40 ligand expression show greatly reduced antibody responses, particularly to protein antigens which require CD4 T_FH cell interactions with B cells. Another expected defect in these individuals would be:

• A) Reduced recruitment of eosinophils by T_H2 cells
• B) Reduced recruitment of neutrophils by T_H17 cells
• C) Reduced production of anti-microbial peptides induced by T_H17 cells
• D) Reduced suppression of dendritic cells by T_reg cells
• E) Reduced activation of macrophages by T_H1 cells

---

Definitions:

Coupon Bond

A debt security that pays interest to the holder on a regular basis until its maturity, when the principal is also repaid.

Maturity

The date when a financial instrument (e.g., bond, loan) reaches its final installment and is to be paid off completely.

Bond Portfolio Management

Bond Portfolio Management involves the strategic buying and selling of bond securities with the goal of achieving a desired return based on an individual's or institution's financial objectives and risk tolerance.

Sidney Homer

A notable economist and author recognized for his work in the fields of bond markets and interest rates.