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The V-D-J Recombination Process Used to Generate Antigen Receptor Diversity

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The V-D-J recombination process used to generate antigen receptor diversity in vertebrates is believed to have evolved from a transposon. How does this hypothesis explain why the recombination signal sequences of the antigen receptor gene segments are joined precisely during the recombination process, whereas the cut ends that are joined to form the antigen receptor coding sequence are joined by an error-prone process?


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