Many Different Viruses Encode Proteins That Function to Down-Regulate MHC

question 26

Multiple Choice

Many different viruses encode proteins that function to down-regulate MHC class I expression on host cells following infection with the virus. This immune evasion mechanism allows the virus to hide from CD8 T lymphocytes that normally detect virus-infected cells by using their T cell antigen receptor to recognize viral peptides bound to MHC class I proteins on the surface of the infected cell. To counteract this immune evasion strategy, NK cells have:

• A) Activating receptors that recognize MHC class I proteins
• B) A mechanism to secrete antiviral peptides
• C) Inhibitory receptors that recognize viral capsid proteins
• D) Activating receptors that recognize viral capsid proteins
• E) Inhibitory receptors that recognize MHC class I proteins

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Definitions:

Amniotic Cavity

The fluid-filled space within the amniotic sac, surrounding and protecting the developing fetus during pregnancy.

Fetus

A developing human from approximately the end of the eighth week after conception until birth.

Prenatal Development

The process of growth and development within the womb from the formation of an embryo through to the development of a fetus until birth.

Central Nervous System

The Central Nervous System (CNS) is comprised of the brain and spinal cord, functioning as the main processing center for the entire nervous system, controlling thoughts, movements, and bodily functions.