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Neutrophils Regulate the Production of Active Cathelicidins (A Class of Antimicrobial

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Neutrophils regulate the production of active cathelicidins (a class of antimicrobial peptides) by segregating the inactive propeptide from the processing enzyme that cleaves and activates it in two different types of cytoplasmic granules. These two types of granules are induced to fuse with phagosomes after ingestion of microbes, bringing the processing enzyme and the propeptide together.


Definitions:

Gender Typing

The method through which a child recognizes their own gender identity and subsequently aligns their behavior, adopting the values and characteristics typical of the gender they associate with.

Secondary Sex Characteristics

Physical features that distinguish the sexes of a species, emerging at puberty but not directly involved in reproduction, such as facial hair in males or breasts in females.

Menarche

The first occurrence of menstruation in a female, marking the onset of fertility.

Androgyny

Androgyny is a state or condition in which an individual possesses both masculine and feminine characteristics, qualities, or traits.

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