Although the Complement Cascade Can Be Initiated by Antibodies Bound

question 9

Multiple Choice

Although the complement cascade can be initiated by antibodies bound to the surface of a pathogen, complement activation is generally considered to be an innate immune response. This is because:

• A) Two of the three pathways for complement activation are initiated by constitutively produced recognition molecules that directly interact with microbial surfaces.
• B) When the complement cascade leads to the formation of a membrane-attack complex, the pathogen is killed.
• C) Several of the soluble products generated by complement activation lead promote the inflammatory response.
• D) Complement proteins bound to the pathogen promote uptake and destruction by phagocytic cells.
• E) The C3 convertase is only produced when complement activation is initiated by antibody binding to a pathogen.

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