Dilated Cardiomyopathy (DCM) Is a Common Cause of Sudden Death

question 76

Multiple Choice

Dilated cardiomyopathy (DCM) is a common cause of sudden death and heart failure. Many mutations can cause DCM, but several of them are linked to the protein troponin, which is an essential protein that helps regulate muscle contraction in the heart.
-The A159E mutation causes an A amino acid to be replaced with an E amino acid (their structures are shown here) . What type of mutation is the A159E mutation?

• A) missense mutation
• B) silent mutation
• C) frameshift mutation
• D) nonsense mutation

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