In Colorectal Cancer, Several Genes Must Be Mutated in Order

question 15

Multiple Choice

In colorectal cancer, several genes must be mutated in order to contribute to a cell developing into a cancer cell, supporting Knudsen's hypothesis. Which of the following kinds of genes would you expect to be mutated?

• A) genes coding for enzymes that act in the colon
• B) genes involved in control of the cell cycle
• C) genes that are especially susceptible to mutation
• D) the same genes that Knudsen identified as associated with retinoblastoma
• E) the genes of the bacteria that are abundant in the colon

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