During DNA Replication

question 84

Multiple Choice

During DNA replication,

• A) all methylation of the DNA is lost at the first round of replication.
• B) DNA polymerase is blocked by methyl groups, and methylated regions of the genome are therefore left uncopied.
• C) methylation of the DNA is maintained because methylation enzymes act at DNA sites where one strand is already methylated and thus correctly methylates daughter strands after replication.
• D) methylation of the DNA is maintained because DNA polymerase directly incorporates methylated nucleotides into the new strand opposite any methylated nucleotides in the template.
• E) methylated DNA is copied in the cytoplasm, and unmethylated DNA is copied in the nucleus.

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Definitions:

D-Glucopyranose

The cyclic form of glucose, a six-membered ring (pyranose) structure, where the hydroxyl group at carbon 1 is in the same orientation as the CH2OH moiety.

Stereochemistry

The study of the spatial arrangements of atoms in molecules and the impact of these arrangements on the physical and chemical properties of those molecules.

α-Pyranose

A form of monosaccharide that adopts a cyclic six-membered ring structure, resembling a pyran, with the anomeric carbon in the alpha configuration.

Haworth Structure

A method for representing cyclic sugars as planar rings with hydroxyl groups positioned above or below the plane.