Suppose That an Error in Transcription Alters the Formation of a Single

question 71

Multiple Choice

Suppose that an error in transcription alters the formation of a single tRNA molecule in a cell. The altered tRNA still attaches to the same amino acid (Phe) , but its anticodon loop has the sequence AAU, which binds to the mRNA codon UUA (usually specifying leucine, Leu) . What will be the effect on translation in this cell?

• A) The altered tRNA will cause this mRNA to make only nonfunctioning product.
• B) The tRNA-Leu will not be able to enter the ribosome to bind to the UUA codon.
• C) One altered tRNA molecule will be relatively inconsequential because it will compete with many "normal" ones.
• D) The altered tRNA will be so unstable that it will not participate in translation.
• E) The altered tRNA will result in an amino acid variant in all copies of the protein.

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