Which Small-Scale Mutation Would Be Most Likely to Have the Greatest

question 36

Multiple Choice

Which small-scale mutation would be most likely to have the greatest negative effect on the functioning of a protein?

• A) a base substitution
• B) a base deletion near the start of a gene
• C) a base deletion near the end of the coding sequence, but not in the terminator codon
• D) deletion of three bases near the start of the coding sequence, but not in the initiator codon
• E) a base insertion near the end of the coding sequence, but not in the terminator codon

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Definitions:

Chromosomes

Thread-like structures located inside the nucleus of animal and plant cells, made of protein and a single molecule of DNA, carrying genetic information.

Cerebral Cortex

The outer layer of the cerebrum in the brain, playing a key role in memory, attention, perception, cognition, awareness, thought, language, and consciousness.

MRI Scans

A medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body.

Longitudinal Study

A study in which people (or animals) are followed and periodically reassessed over a period of time.