Phenylephrine (PE, See the Structure Below) Is a Nasal Decongestant

question 28

Multiple Choice

Phenylephrine (PE, see the structure below) is a nasal decongestant and is the active ingredient in Sudafed, which contains phenylephrine hydrochloride (PEHCl) . This conjugate acid of phenylephrine (PEH^) has a pK_a  5.5. At a physiological pH of 7.4, what is the ratio of concentrations, [PE]/[PEH^]?

• A)6.7
• B)0.01
• C)0.14
• D)79
• E)21

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