Giardia Intestinalis Can Cause Disease in Several Different Mammalian Species

question 9

Multiple Choice

Giardia intestinalis can cause disease in several different mammalian species, including humans. Giardia organisms (G. intestinalis) that infect humans are similar morphologically to those that infect other mammals, thus they have been considered a single species. However, G. intestinalis has been divided into different subgroups based on their host and a few other characteristics.
In 1999, a DNA sequence comparison study tested the hypothesis that these subgroups actually constitute different species. The following phylogenetic tree was constructed from the sequence comparison of rRNA from several subgroups of G. intestinalis and a few other morphologically distinct species of Giardia. The researchers concluded that the subgroups of Giardia are sufficiently different from one another genetically that they could be considered different species. (T. Monis, et al. 1999. Molecular systematics of the parasitic protozoan Giardia intestinalis. Mol. Biol. Evol. 16[9]:1135-44.)
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By examining the phylogenetic tree diagrammed in the figure above, what conclusion can you draw about the species G. microti?

• A) It evolved before G. intestinalis.
• B) It is more closely related to G. muris than to G. intestinalis.
• C) It should not be labelled a species distinct from G. intestinalis.
• D) It is part of a monophyletic group that also includes G. intestinalis.

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