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HIV's Genome of RNA Includes the Code for Reverse Transcriptase

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HIV's genome of RNA includes the code for reverse transcriptase (RT) , an enzyme that acts early in infection to synthesise a DNA genome off of an RNA template. The HIV genome also codes for protease (PR) , an enzyme that acts later in infection by cutting long viral polyproteins into smaller, functional proteins. Both RT and PR represent potential targets for antiretroviral drugs. Drugs called nucleoside analogues (NA) act against RT, whereas drugs called protease inhibitors (PI) act against PR.
Which mechanism produces variation for evolution by shuffling existing alleles?


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