The Following Microarray Data Are Shown for Four Human Genes

question 36

Multiple Choice

The following microarray data are shown for four human genes.Two samples were hybridized to the microarray in this experiment.One sample was cDNA generated from mRNA of a tissue culture cell line that was originally derived from a B-cell leukemia.The other sample was cDNA generated from normal, mature neural tissue. - Vertical stripes mean hybridization to cancerous B-cell cDNA only.
- Horizontal stripes mean hybridization to normal neural cell cDNA only.
- Completely filled in means hybridization to both cDNA types.
- Blank means hybridization to neither cell's cDNA. The gene sequences contained in spot 2 are present only in the B-cell cancer sample.What is a possible function for this gene, based on the microarray data?

• A)This gene may be involved in neurotransmitter release at the synapse since B cells are known to be involved in cell-to-cell signaling.
• B)This gene may be involved in activating cell growth, so it is switched on in the cancer cell line that is growing rapidly.
• C)This gene is involved in the immune function of the B cell because that is the cell type from which this cancer line was initially derived.
• D)This gene may be involved in neurotransmitter release at the synapse since B cells are known to be involved in cell-to-cell signaling, and it may also be involved in activating cell growth, so it is switched on in the cancer cell line that is growing rapidly.
• E)This gene may be involved in activating cell growth, so it is switched on in the cancer cell line that is growing rapidly, and it is also involved in the immune function of the B cell because that is the cell type from which this cancer line was initially derived.

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Definitions:

Police Power

The ability of a state to control behavior and ensure lawfulness within its territory to improve the health, safety, ethics, and overall well-being of its citizens.

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A legal principle that protects an individual from being unlawfully detained, allowing them to seek a judicial hearing to challenge the legality of their detention or imprisonment.

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Characteristic of something that poses a risk or threat to safety, health, or well-being.

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