Once a Chromosomal Position for a Putative Gene Associated with Parkinson

question 21

Multiple Choice

Once a chromosomal position for a putative gene associated with Parkinson disease is verified, which of the following is a next step?

• A)developing a FISH screening test to identify pre-Parkinson patients
• B)determining whether this locus is mutated in all Parkinson patients
• C)using a genome-wide linkage SNP panel to identify more minor genes
• D)ascertaining all living and at-risk individuals who are family members of the affected test subjects
• E)fine mapping of the linkage region to identify particular variants for influencing risk

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