In Leber's Disease (LHON), Degeneration of the Optic Nerve Results

question 39

Multiple Choice

In Leber's disease (LHON) , degeneration of the optic nerve results in blindness due to a defect in NADH dehydrogenase affecting electron transport. If this is due to a mutation in a mitochondrial gene, which combination of the following effects would you expect to see when doing a pedigree analysis of a family with LHON? i. variable expressivity
Ii. incomplete penetrance
Iii. progressive blindness over time
Iv. maternal inheritance
V. diminished muscle mass

• A)i and ii only
• B)ii and iii only
• C)iii and iv only
• D)i, ii, iii, and v only
• E)i, ii, iii, and iv only

Understand the genetic basis of certain personality traits.

Discuss the reliability and validity of personality assessments.

Explore the dynamics between personality traits and situational behavior.

Understand the concept and types of job crafting and how they influence work outcomes.

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Definitions:

Glial Cells

Non-neuronal cells in the central nervous system and the peripheral nervous system that do not produce electrical impulses but serve important support functions for neurons.

Neurons Together

A phrase indicating the collective function or interaction of neurons, which are the basic working units of the brain and nervous system, responsible for receiving, processing, and transmitting information through electrical and chemical signals.

Axon

The slender, tail-like extension of the neuron that transmits signals to the dendrites or cell body of other neurons and to muscles, glands, and other parts of the body.

Soma

The cell body of a neuron, which contains the nucleus and is essential for the neuron's metabolic and repair processes.