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A significant polymorphic inversion on chromosome 17, the MAPT inversion, is identified by marker SNPs that can now be used to screen large numbers in a population. The inverted region is large and extends for approximately 900 kb. The two haplotypes (one inverted and one not) are each associated with increased risk of a number of neurological conditions. How can the inverted region be used to find the most recent common ancestor of the inversion?
Reinforcing Position
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