During DNA Replication in E

question 4

Multiple Choice

During DNA replication in E. coli, what is the role of DnaA?

• A)DnaA is a region of DNA recognized by the replisome where replication is initiated.
• B)DnaA bends DNA, hydrolyzing the hydrogen bonds in the 13-mer region of oriC and creating an open complex.
• C)DnaA is a helicase that uses ATP to hydrolyze hydrogen bonds and separate DNA strands.
• D)DnaA carries the helicase protein to the open region of DNA where hydrolysis and strand separation will occur.
• E)DnaA prevents reannealing of the separated strands so replication can proceed.

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