E Coli RNA Polymerase (RNAP) Has No 3' to 5

question 15

Multiple Choice

E. coli RNA polymerase (RNAP) has no 3' to 5' exonuclease activity. Which statement BEST explains why this is not a required activity for this enzyme?

• A) RNAP makes fewer errors in NTP addition, so this activity is unnecessary.
• B) RNAP does not need to degrade nucleic acids ahead of the transcription bubble.
• C) Errors in transcription will have no impact on the function of the RNA product.
• D) Multiple RNA products are created and turnover rapidly, so errors have less impact.
• E) None of the statements explains why this is not a required activity.

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