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The DNA of Virtually Every Cell Is Underwound (I

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The DNA of virtually every cell is underwound (i.e., negatively supercoiled) relative to B-form DNA. In bacteria, an enzyme called (a) _____ introduces negative supertwists into DNA using (b) _____ as a source of energy. This enzyme is classified as a type (c) _____, which affects the linking number in steps of (d) _____. The usual substrate for this enzyme within an E. coli cell is the bacterial chromosome. This circular DNA molecule of 4,700,000 base pairs has a linking number of approximately (e) _____ when it is closed and relaxed. This enzyme would (f) _____ (decrease/increase/not change) this linking number when acting upon this DNA molecule in the presence of the above energy source.


Definitions:

Passive Resistances

Nonviolent methods of protest and non-cooperation with authority in order to achieve political or social goals.

Symbolic Reclassification

The process of redefining or reinterpreting symbols, terminologies, or classifications to alter their perceived meaning.

Racialized Dynamics

The process by which racial significance is attributed to relationships, social practices, or group identities.

Multiculturalism Framework

An approach that recognizes, values, and promotes the diversity of cultures within a community or society, advocating for equal respect and rights.

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