In Kohrana's Experiments, a Messenger RNA with the Sequence 5'-UUUUUU…

question 136

Essay

In Kohrana's experiments, a messenger RNA with the sequence 5'-UUUUUU… -3' coded for a polypeptide with the sequence Phe-Phe-Phe-Phe-…. (polyphenylalanine). Imagine that he added a single nucleotide bearing the base G to one end of the mRNA. The resulting polypeptide was polyphenylalanine with a single Leu at the carboxyl (-COOH) end. Did Kohrana add the G to the 5' or the 3' end of the mRNA?

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