The Genome of Streptomyces Coelicolor has a High CG Content;

question 55

Multiple Choice

The genome of Streptomyces coelicolor has a high CG content; about 72% of base pairs are GC. Compared with a sequence with 50% G and C, how would the high GC content of S. coelicolor affect the number of fragments obtained by digestion of its DNA with the restriction enzyme DraI (restriction site 5-TTTAAA-3 ) ?

• A)more than would be expected from a random sequence
• B)less than would be expected from a random sequence
• C)approximately the same number that would be expected from a random sequence
• D)It is not possible to determine from the information provided.

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