Find the minimum cost solution for the transportation problem detailed in the table below. 
Before your solution can be implemented,you discover that the combination Source 3 - Destination 1 is unavailable,due to political turmoil in the country where Source 3 is located.Solve the revised problem.How much is cost increased by this complication?
Definitions:
Production Costs
The total expense incurred in manufacturing goods or providing services, including raw materials, labor, and overhead expenses.
Chemicals
Substances used in or produced by chemical processes, often referring to compounds or materials in industrial, scientific, or consumer products.
Labor
The effort of humans, encompassing both mental and physical work, utilized in creating goods and services.
Effluent Fee
A charge levied on the quantity of pollution discharged into the environment, aiming to control environmental pollution.
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