Trans-Synaptic Tracing Uses Rabies Virus to Spread Across Synapses

question 24

Multiple Choice

Trans-synaptic tracing uses rabies virus to spread across synapses. In the scenario in Figure, what would happen if the presynaptic cell also expressed the glycoprotein transgene? Figure

• A) The virus spread would not be limited to presynaptic neurons of the starter cells.
• B) The virus would not be limited to how many neurons it could infect.
• C) The virus would not be able to infect other synaptic partners and would stay in the neuron presynaptic to the starter neuron.
• D) The virus would not be able to spread to any synaptic partners and would stay in the starter cell.

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