The Kinase LKB1 (Par4) Was First Identified in C

question 25

Essay

The kinase LKB1 (Par4) was first identified in C. elegans as a factor required for asymmetric cell division/fate in the early embryo: PAR4 mutant cells divide symmetrically, resulting in early lethality. If the role of Par4 is similar in both contexts, what might you expect to observe by staining early C. elegans embryos with an antibody to this protein?

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