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AWhat Is the Maximum Number of MHC Class I and Class

question 44

Essay

A.What is the maximum number of MHC class I and class II molecules that a heterozygous individual could theoretically express? Explain your answer.(Ignore the possibility of MHC class II molecules composed of chains from different isotypes.)
B.How does this relatively small number of MHC molecules have the potential to bind the huge number of antigenic peptides encountered in the environment,and what features of a peptide determine whether it will be bound by a given MHC molecule?


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