How Successful Have Genomewide Association Studies Been in Identifying Genetic

question 40

Essay

How successful have genomewide association studies been in identifying genetic susceptibility to complex disease? What has been the main value of these studies?

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Definitions:

Interphalangeal

Pertaining to the joints between the phalanges, the bones in the fingers and toes.

Metacarpophalangeal

Refers to the joints between the metacarpal bones and the phalanges (fingers) of the hands, supporting movement such as bending.

Tibiotalar

Referring to the joint formed between the tibia (shinbone) and the talus (ankle bone), crucial for ankle movement.

Tarsometatarsal

Referring to the joint connections between the tarsal bones of the foot and the metatarsal bones of the forefoot.