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One way our bodies produce ATP is to couple the formation of ATP from ADP with the hydrolysis of phosphoenopyruvate (PEP) ,as shown below. PEP + ADP + H+(aq) → pyruvate + ATP ΔrG°′ = ?
Given the following thermodynamic data,
PEP + H2O(l) → pyruvate + HPO42-(aq)
ΔrG°′ = −61.9 kJ/mol-rxn
ATP + H2O(l) → ADP + HPO42-(aq) + H+(aq)
ΔrG°′ = −30.5 kJ/mol-rxn
Calculate the standard Gibbs free energy of reaction for the formation of ATP from the hydrolysis of PEP.
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