Cells Have Oligosaccharides Displayed on Their Cell Surface That Are

question 22

Multiple Choice

Cells have oligosaccharides displayed on their cell surface that are important for cell-cell recognition.Your friend discovered a transmembrane glycoprotein, GP1, on a pathogenic yeast cell that is recognized by human immune cells.He decides to purify large amounts of GP1 by expressing it in bacteria.To his purified protein he then adds a branched 14-sugar oligosaccharide to the asparagine of the only Asn-X-Ser sequence found on GP1 (Figure 15-32) .Unfortunately, immune cells do not seem to recognize this synthesized glycoprotein.Which of the following statements is a likely explanation for this problem? Figure 15-32

• A)The oligosaccharide should have been added to the serine instead of the asparagine.
• B)The oligosaccharide should have been added one sugar at a time.
• C)The oligosaccharide needs to be further modified before it is mature.
• D)The oligosaccharide needs a disulfide bond.

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Definitions:

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An experimental design where a single group of participants is measured before and after an intervention, lacking a control group for comparison.

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One-shot Case Study

An experimental design where a single group is exposed to a treatment and then measured to assess its effect, lacking a control group for comparison.

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Patterns and practices that are conducive to effective learning and information retention.