The Mouse Genome Consists of 2,700 Mb

question 10

Multiple Choice

The mouse genome consists of 2,700 Mb. A genomic library is constructed using BAC vectors and overlapping fragments of the mouse genome. The average size of the mouse DNA inserts is 200 kb.
-A mouse genomic library is constructed so that the number of clones equals one genomic equivalent.Is it likely that this library contains the entire mouse genome?

• A)No; by chance some parts of the genome will be represented more than once and others not at all.
• B)Yes; that is a sufficient number clones for every part of the genome to be represented one time.
• C)No; the restriction enzyme used to fragment the genome will delete some DNA on the ends of clones.

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