What Would Be the Consequences of a Two Nucleotide-Deletion Mutation

question 18

Multiple Choice

What would be the consequences of a two nucleotide-deletion mutation in the middle of the first exon of a protein-coding gene?

• A) The result would be no change in the protein, since deletions are very rare.
• B) A reading frameshift would occur. All codons (and thus amino acids) downstream of the codon in which the deletion occurred would be different, including the stop signal.
• C) Some codons might be altered since there are changes in the bases of the DNA, but the stop codon would remain the same and the protein would still be made.
• D) Since exons are not coding regions, no changes in the protein would occur.
• E) No change in the reading frame would occur due to the degeneracy of the genetic code.

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