A Woman and Her Husband Have a Child Affected with Maple

question 1

Multiple Choice

A woman and her husband have a child affected with maple syrup urine disease (MSUD) . The woman subsequently has an affair and becomes pregnant, but the father of this baby cannot be contacted for genetic testing. What information would be used to determine the risk of MSUD in the second child?

• A) Mutation rate for the MSUD genes
• B) Carrier frequency for MSUD mutations in the general population
• C) Carrier frequency for MSUD mutations in the appropriate ethnic population
• D) The risk can be calculated based on the mother's genotype alone
• E) The risk cannot be calculated with reasonable accuracy

---

Definitions:

Decreased

Reduced in quantity, size, or intensity.

Preventive Medications

Drugs used to prevent the onset of diseases or conditions before they occur.

Inhalers

Medical devices used to deliver medication in the form of a mist inhaled into the lungs, commonly used for treating respiratory conditions like asthma.

Asthma Patients

Individuals diagnosed with asthma, a respiratory condition marked by spasms in the bronchi of the lungs, causing difficulty in breathing.