The Marking of a Protein by Polyubiquitylation to Signify Degradation

question 25

Multiple Choice

The marking of a protein by polyubiquitylation to signify degradation …

• A) requires the hydrolysis of one ATP molecule to ADP per polyubiquitin chain.
• B) involves covalent attachment of the target protein to the E1 enzyme.
• C) is carried out by the proteasome complex.
• D) is typically done on an arginine residue in the target protein.
• E) involves the recognition of the target protein by an E2-E3 ligase.

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Definitions:

Paired Appendages

Structures that extend from the body of an organism and occur in matching pairs, such as wings, arms, and legs.

Watery Habitats

Environments characterized by the presence of water, such as rivers, lakes, wetlands, and oceans, which support a diverse range of life.

Notochord

Stiff rod of connective tissue that runs the length of the body in chordate larvae or embryos.

Tunicates

Marine invertebrates with a sac-like body, filter-feeding mechanism, and notochord during the larval stage; also known as sea squirts.