In a Gene That Normally Contains Three Exons, Which of the Following

question 15

Multiple Choice

In a gene that normally contains three exons, which of the following changes probably will NOT activate the nonsense-mediated mRNA decay pathway? The sizes of exons 1 to 3 are 100, 150, and 200 nucleotide pairs, respectively.

• A) A nonsense mutation in exon 1.
• B) A nonsense mutation in exon 2.
• C) A mutation in the first intron resulting in the inclusion of a large intronic fragment in the mature mRNA.
• D) A frameshift mutation in exon 1.
• E) A mutation in exon 2 leading to its loss through exon skipping.

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Definitions:

Equilibrium Rental Price

The price at which the quantity of rental properties supplied equals the quantity demanded.

Quota Rent

The earnings exceeding the normal anticipated returns due to import or export quotas.

Deadweight Loss

A decrease in economic effectiveness occurring when a good or service doesn't reach its free market equilibrium.

Minimum Wage

The lowest legal hourly rate of pay that employers can compensate workers, established to protect employees from exploitation.