Some Viruses Encode a Protease That Cleaves the Translation Initiation

question 17

Multiple Choice

Some viruses encode a protease that cleaves the translation initiation factor eIF4G, rendering it unable to bind to eIF4E. What is the consequence of this cleavage?

• A) It shuts down most of the cellular translation machinery, which causes the release of virus particles.
• B) It favors viral protein synthesis because IRES-dependent translation initiation is inhibited.
• C) It shuts down most host-cell protein synthesis and diverts the translation machinery to IRES-dependent initiation, thus favoring viral protein synthesis.
• D) It favors viral protein synthesis by shutting down translation from uORFs.
• E) It shuts down IRES-dependent translation, forcing the virus into latency.

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Definitions:

Imitated

Reproduced someone's behavior, speech, or actions, often as a way of learning, showing admiration, or mocking.

Aggressive

Behavior characterized by physical or verbal actions intended to hurt, threaten, or intimidate others.

Complex

A system or problem consisting of interconnected parts, characterized by its difficulty to understand, predict, or solve.

Production Processes

The methods and operations involved in the transformation of raw materials into finished goods or products.