The nicotinic acetylcholine receptor is a cation channel in the plasma membrane of some neurons. It is composed of five subunits, each of which is a transmembrane protein. The hydropathy plot for each mature subunit is qualitatively represented in the following diagram. How many membrane-spanning alpha helices do you expect to exist in each subunit?
Definitions:
Composition
The arrangement or makeup of something, often referred to in the context of artistic elements or financial mixtures.
Subordination
A ranking of priorities in claims for ownership or interest; often used in debt agreements to determine the sequence of payments.
Extension
In finance, an agreement to extend the maturity date or due date of a financial instrument or loan.
Insolvency
A financial condition where an individual or entity cannot meet their debt obligations as they come due.
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