What Is the Effect of Defective or Missing N-Acetylglucosamine Phosphotransferase

question 51

Multiple Choice

What is the effect of defective or missing N-acetylglucosamine phosphotransferase on lysosomal protein sorting?

• A) Lysosomal proteins are secreted from the cell.
• B) Lysosomal proteins are retained in the Golgi network.
• C) Lysosomal proteins are retained in the ER.
• D) Lysosomal proteins remain tightly bound to M6P receptors.
• E) Nonfunctional lysosomal proteins accumulate in the lysosome.

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