Which of the Following Proteins Activates the Mitochondrial Pathway of Apoptosis

question 12

Multiple Choice

Which of the following proteins activates the mitochondrial pathway of apoptosis?

• A) The tumor suppressor protein p53, when activated in response to extensive DNA damage.
• B) The BH3-only protein Bid, when cleaved by the initiator caspase-8 (from the extrinsic pathway).
• C) The anti-IAP protein Omi, when activated by dephosphorylation.
• D) The BH3-only protein Bad, when activated by dephosphorylation.
• E) All of the above.

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Definitions:

Defined Contribution Plan

A retirement plan where the employer, employee, or both contribute to an individual's account, and the retirement benefits depend on the account's investment performance.

Risk-free Return

The theoretical return on an investment with zero risk of financial loss, often represented by the yield on government securities.

Defined Contribution Plan

A retirement plan where both the employee and employer contribute to an account, with the final benefit dependent on account performance.

Risk-free Return

The theoretical return on an investment with no risk of financial loss, typically less than the return on riskier investments.