Which of the Following Proteins Activates the Mitochondrial Pathway of Apoptosis

question 12

Multiple Choice

Which of the following proteins activates the mitochondrial pathway of apoptosis?

• A) The tumor suppressor protein p53, when activated in response to extensive DNA damage.
• B) The BH3-only protein Bid, when cleaved by the initiator caspase-8 (from the extrinsic pathway).
• C) The anti-IAP protein Omi, when activated by dephosphorylation.
• D) The BH3-only protein Bad, when activated by dephosphorylation.
• E) All of the above.

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Definitions:

DSM-5

The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, is a guide for diagnosing mental disorders.

Major Depressive Episode

A period of at least two weeks during which a person experiences a depressed mood or loss of interest or pleasure in nearly all activities.

Informed Consent

A process ensuring that a participant is fully aware of and understands the potential risks and benefits involved in a therapeutic or clinical intervention before agreeing to partake.

Decisional Capacity

The capability of an individual to make informed, independent decisions about their own healthcare or personal matters.