The Requirement for Accumulation of Multiple Mutations in Cancer Progression

question 42

Short Answer

The requirement for accumulation of multiple mutations in cancer progression is manifested in the normalized percentage of new cases of cancer diagnosed in different age groups. Which of the curves A to E in the following graph better represents the incidence of human cancers as a function of age?

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Definitions:

Ratify

The official approval or confirmation of a treaty, contract, or agreement, making it valid and binding.

Contract

A legally binding agreement between two or more parties that outlines the terms and conditions of a particular arrangement or transaction.

Affirm

To confirm, ratify, or declare positively, often in a legal context such as affirming a judgment.

Ratifies

To formally approve or confirm something, often an agreement or treaty, making it officially valid.