The Following Southern Blot Was Performed to Examine a Mutation

question 1

Multiple Choice

The following Southern blot was performed to examine a mutation that is linked to a genetic disease.The blot was probed with fluorescent-labeled cDNA of the gene.What is the most likely explanation for the abnormal bands in the patient in comparison with the normal control?

• A)Faulty splicing of the messenger RNA (mRNA).
• B)The deletion of an entire exon.
• C)A single-nucleotide polymorphism.
• D)Duplication of at least one exon.
• E)The expansion of a microsatellite.

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Definitions:

Loanable Funds

A concept in economics that describes the market where borrowers and lenders meet to transact loans or bonds.

Nominal Interest Rate

The interest rate before adjustments for inflation; the rate quoted by financial institutions.

Real Interest Rate

The interest rate that has been adjusted to remove the effects of inflation, reflecting the real cost of funds to the borrower and the real yield to the lender.

Inflation

The rate of increase in the general price level for goods and services, leading to a decline in buying power.