The Figure Shows Routine Histologic and Immunofluorescence Images of a Kidney

question 8

Multiple Choice

The figure shows routine histologic and immunofluorescence images of a kidney biopsy specimen taken from a 53-year-old man with acute-onset renal failure and hemoptysis (coughing up blood) .The histologic section is notable for glomerular inflammation in a crescentic distribution.Staining,using fluorescently tagged anti-IgG antibody,shows linear deposits of IgG along the glomerular basement membrane.Urinalysis is positive for moderate proteinuria and red cell casts.A chest radiograph shows pulmonary infiltrates.Which of the following is the most likely diagnosis?

• A)Systemic lupus erythematosus
• B)Graves' disease
• C)Chronic allograft rejection
• D)Goodpasture's syndrome
• E)Poststreptococcal glomerulonephritis

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Definitions:

Living Lineages

Sequences of living organisms that are descended from a common ancestor, showcasing the path of evolution.

Mammals

A class of warm-blooded vertebrate animals characterized by the presence of mammary glands, hair or fur, and a neocortex.

Unique Feature

a distinct characteristic or element noticeable in a person, object, or place that sets it apart from others.

Evolutionary Pathway

A sequence of genetic, structural, or functional changes that occur in a biological lineage over time leading to diversification and speciation.