Mycophenolate Mofetil Is a Cytotoxic Drug That Is Commonly Used

question 11

Multiple Choice

Mycophenolate mofetil is a cytotoxic drug that is commonly used in patients receiving kidney transplants, as part of a combination therapy with other immunosuppressive drugs. Studies have been performed to assess whether reductions in mycophenolate mofetil dose given to transplant patients starting around 4 months post-transplant have deleterious effects on the transplanted kidney function or on episodes of graft rejection. The motivation for this type of study is:

• A) The high expense of combination therapies that require multiple different drugs
• B) The side effects of the cytotoxic drug on healthy dividing cells in the body
• C) The convenience to the transplant patient of fewer medications to take on a daily basis
• D) The off-target effects of mycophenolate mofetil on non-dividing cells
• E) The possibility that transplant patients develop an allergic reaction to the mycophenolate mofetil

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