Examlex
Treg cells that express FoxP3 are generally thought to have T-cell receptors that recognize self-peptides bound to MHC class II molecules. In the skin, keratin and filaggrin are among the self-antigens expressed. FoxP3+ Treg cells found in skin and skin-draining lymph nodes might be specific for the self-antigen, filaggrin. These FoxP3+ filaggrin-specific Treg cells:
Hibernate
A state of inactivity and metabolic depression in animals during winter, allowing survival through periods of reduced food availability.
Cold-blooded
Refers to organisms, such as reptiles and fish, that do not regulate their body temperature internally but rely on external sources.
Metabolism
The set of life-sustaining chemical reactions in organisms to convert food to energy, maintain cellular structure, and grow.
Brain-Wave Patterns
The fluctuations in electrical activity within the brain, as detected by electroencephalography, which differ during various states of consciousness.
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