Proteins Found in the Circulation Travel Throughout the Body, Including

question 30

Multiple Choice

Proteins found in the circulation travel throughout the body, including the thymus. One example is serum albumin. Developing T cells with T-cell receptors specific for peptides of human serum albumin bound to MHC class II molecules would likely be:

• A) Positively selected and would mature into CD4 T cells
• B) Positively selected and would mature into CD8 T cells
• C) Negatively selected in the thymus and deleted from the mature repertoire
• D) Targeted for peripheral mechanisms of self-tolerance after emigrating from the thymus
• E) Excluded from the T cell zones of the spleen after emigrating from the thymus

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