Two Distinct Lineages of T Cells Can Be Identified Based $\alpha$

question 3

Multiple Choice

Two distinct lineages of T cells can be identified based on their expression of $\alpha$ : $\beta$ versus $\gamma$ : $\delta$ T-cell receptors. A deficiency in the signaling receptor Notch1 would result in:

• A) A loss of \(\alpha\):\(\beta\) but not \(\gamma\):\(\delta\) T cells
• B) A loss of both of \(\alpha\):\(\beta\) and \(\gamma\):\(\delta\) T cells
• C) A loss of \(\alpha\):\(\beta\) T cells and a massive expansion of \(\gamma\):\(\delta\) T cells
• D) An increased number of both of \(\alpha\):\(\beta\) and \(\gamma\):\(\delta\) T cells
• E) A normal number of both of \(\alpha\):\(\beta\) and \(\gamma\):\(\delta\) T cells

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